Sometime after his duel with Shimura, Jin comes across a community of villagers who have been driven insane by a poison described as "sacred medicine". It was administered to them by a warband of Mongols whom Jin has never previously encountered: members of the Mongolian Eagle Tribe, led by Ankhsar "The Eagle" Khatun (Anzu Lawson). Defeating the warband, Jin learns that Khatun is engaged in a conquest of Iki Island, where his late father Kazumasa had once led an unsuccessful military campaign against the island's raiders. The samurai withdrew from the island after Kazumasa was ambushed and killed by the raiders. Jin was there during the campaign as a boy; he witnessed his father's death and still blames himself for not saving him. Made cognizant of this new threat to Tsushima, Jin sails to Iki Island to stop Khatun and face his past.